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Help CenterPharmaceutical Multi-effect Crystallizing Evaporator for Drug Purification, GMP Compliant, 304 SS
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Welcome to Qingdao Conqinphi Environmental Technology Group Co., Ltd. As a leading manufacturer established in 2015, we specialize in advanced environmental and pharmaceutical process equipment. Our Pharmaceutical Multi-effect Crystallizing Evaporator for Drug Purification is engineered to meet the highest standards of purity, efficiency, and regulatory compliance. Operating out of a 10,000-30,000 square meter factory in Qingdao, China, we have a dedicated team of 201-300 employees and an annual export value exceeding US$10 million. This crystallizing evaporator is the ideal solution for pharmaceutical companies seeking to optimize drug purification, recover valuable solvents, and ensure GMP-compliant production.
Product Overview & Core Features
This multi-effect crystallizing evaporator is designed for continuous or batch processing of pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It integrates evaporation and crystallization in a single, closed-loop system, minimizing product loss and energy consumption. Key features include:
- Multi-effect Design: Utilizes vapor from one effect to heat the next, reducing steam consumption by up to 60% compared to single-effect evaporators.
- GMP-Compliant Construction: All product-contact surfaces are made of 304 stainless steel with a high-grade surface finish (Ra ≤0.4μm), ensuring easy cleaning and preventing contamination.
- Precision Crystallization Control: Equipped with advanced temperature and vacuum control systems to achieve uniform crystal size and high purity yields.
- Solvent Recovery Capability: Built-in condenser system recovers solvents (e.g., ethanol, methanol, acetone) for reuse, lowering operational costs.
- Automation & Safety: PLC-controlled with HMI touchscreen, enabling real-time monitoring of pressure, temperature, and flow. Multiple safety interlocks are incorporated.
- Customizable Configuration: Available in 2-effect, 3-effect, or more, depending on your production volume and energy efficiency requirements.
Technical Specifications
The following table presents typical parameters for a standard 3-effect unit. Customizations are available upon request.
| Parameter | Value |
| Evaporation Capacity | 200 – 5,000 L/h (custom) |
| Operating Temperature | 40°C – 120°C |
| Vacuum Degree | -0.08 – -0.095 MPa |
| Steam Consumption Reduction | Up to 60% vs single effect |
| Material of Construction | 304 SS (316L optional) |
| Surface Finish | Ra ≤0.4μm (internal) |
| Control System | PLC + HMI (Siemens or equivalent) |
| Power Supply | 380V / 50Hz / 3-phase (other voltages available) |
Advantages for Your Production
- Higher Purity Yield: The controlled crystallization process ensures high purity and consistent crystal morphology, critical for pharmaceutical drug purification.
- Energy & Cost Savings: Multi-effect design drastically reduces steam and cooling water usage, lowering total cost of ownership.
- Compliance Assurance: Our equipment meets GMP guidelines and is manufactured under ISO9001, ISO14000, and OHSAS18001 certified processes.
- Reliable Long-term Operation: Over 8 years of export experience to North America, Europe, Southeast Asia, and more, with a proven track record of reliability.
Trusted Partnership – Why Choose Us
As a company with an annual export value of US$10–50 million and a factory spanning 10,000–30,000 m², we have the capacity and expertise to deliver large-scale projects. Our certifications include HACCP, TL900, QS9000, SA8000, and multiple ISO standards (ISO9000 series, ISO14000, ISO17799, etc.), reflecting our commitment to quality, safety, and environmental responsibility. We have served clients in over 50 countries, including North and South America, Eastern and Western Europe, the Middle East, Africa, and Oceania. Every unit is tested before shipment, and we offer comprehensive after-sales support including installation guidance, training, and spare parts. Contact us today to discuss your specific purification requirements and let our team engineer a solution that exceeds your expectations.
Frequently Asked Questions (FAQ)
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Q: What is the main advantage of a multi-effect crystallizing evaporator over a single-effect unit?
A: Multi-effect designs reuse vapor from one effect to heat subsequent effects, reducing steam consumption by 50–60% and lowering operating costs significantly, while still achieving high-purity crystallization. -
Q: Is this equipment suitable for API (active pharmaceutical ingredient) purification?
A: Yes, it is specifically designed for pharmaceutical applications, including API purification, solvent recovery, and removal of impurities. The GMP-compliant construction ensures no cross-contamination. -
Q: Can the material be upgraded to 316L stainless steel for corrosive media?
A: Absolutely. While the standard is 304 SS, we can manufacture with 316L, 904L, or other alloys depending on your process chemistry. Please specify when ordering. -
Q: What is the typical delivery lead time?
A: For a standard unit, lead time is approximately 45–60 days. Customized designs may require 60–90 days, depending on complexity. We can expedite for urgent orders. -
Q: Do you provide installation and commissioning support?
A: Yes, we offer remote guidance or on-site commissioning (additional cost). Our technical team will train your operators to ensure smooth startup and optimal performance. -
Q: Which certifications does your equipment hold?
A: Our manufacturing facility is certified under ISO9001, ISO14000, OHSAS18001, and our products are designed to meet GMP standards. Additional certifications like HACCP are available for related food/pharma processes. -
Q: Can the evaporator handle multiple solvents in one batch?
A: With proper control settings and optional fractionation, it can separate and recover different solvents sequentially. However, we recommend discussing your specific solvent mixture with our engineers for optimal design. -
Q: What is the minimum order quantity (MOQ)?
A: Our MOQ is 1 unit, but we can also accommodate pilot-scale units (e.g., 50 L/h) for R&D purposes. For large production lines, we offer volume discounts.
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